2 A few months later, a second paper in Nature presented the first biomechanical analysis of habitually barefoot runners, showing how they are able to run comfortably without generating an impact peak when the foot hits the ground by either
forefoot or midfoot striking. 3 As barefoot and minimally shod running gained rapid worldwide popularity, a vociferous public debate began. Is it safe? What are the costs and benefits of wearing shoes? How should you run? There remains much disagreement about barefoot running, but the debate has sparked lots of good research that ultimately should yield many benefits. We note that despite a lack of consensus on some key issues, extreme views with little grounding in science have tended to get the most FK228 nmr attention in the popular media. Some advocates have argued that modern shoes cause
injury, while others claim that barefoot running is a dangerous “fad”. Neither of these views is supported by scientific research, and many journalists and advertisers have further confused the issue by conflating actual barefoot running with running in minimal shoes, which are often oxymoronically termed “barefoot shoes”. While dozens of papers have been published in the last few years on barefoot and minimal shoe running, we believe there is much to learn and resolve, so we are pleased to present the first edited issue devoted SAHA HDAC solubility dmso specifically to this topic. At the invitation of Walter Herzog, the issue was jointly edited by Irene Davis, Daniel Lieberman, and Benno Nigg. Because our goal was to solicit high quality, original, peer-reviewed research on the topic, we advertised the issue widely to researchers in the field via listservs and emails. We received 17 submissions, all of which went through rigorous peer-review, resulting in 10 accepted papers that present a wide variety of views and analyses. To briefly summarize the results: Hein and Grau4 showed that habitually shod runners who typically rearfoot strike in cushioned shoes still tend to heel strike but with a slightly flatter foot placement when asked to run barefoot or in minimal shoes on a soft surface made of EVA, the same material used in a shoe’s
heel. Miller and colleagues5 presented a prospective randomized control study that tested how 12 weeks of running in minimal shoes altered Sodium butyrate foot shape and muscle cross-sectional area. They found that minimally shod runners developed significantly stiffer arches with relatively larger cross sections of several intrinsic foot muscles, indicating that the foot adapted to the greater demands required by such shoes. Lieberman6 analyzed running kinematics of Tarahumara Native Americans in Mexico, showing that Tarahumara who wear only minimal shoes showed much variation in running form but were more likely to midfoot strike and forefoot strike than those who wear conventional shoes. This study also found that minimally shod Tarahumara had significantly stiffer arches than conventionally shod Tarahumara.