S considered in the light of the Polo-like kinase potential adverse effects on water consumption. An examination of the patterns of Ver Change of the K Rpergewichts need during the study with the model of the image shows a rapid initial decrease in K Rpergewichts and water intakenitude Ver Changes and the m matched St Rfaktoren effects related to water consumption has declined. Therefore, the h HIGHEST alachlor ESA dose in the study of drinking water as a NOAEL. 3.1.4. Reproduktionstoxizit t ern and development in view of the reported effects on the testes observed in dogs Currency exposure to acetochlor, the potential for reproductive effects was examined closely for the degradation products. Although there are no studies on Reproduktionstoxizit t are available, there was no evidence of effects on reproductive organs within 90 days for a study of the degradation products. Small changes In the weights of the ovaries and testes were observed in the study of drinking water with 91 days of alachlor ESA. A detailed examination of the histopathological reports of this study suggest that 2/10 m had Male pattern of rats in high dose group hypospermatogenesis. One of the two male pattern rat was found dead on study day 13 and found the animal had negligible water Ssigbar need during the first week of the study 3-Methyladenine PI3K Inhibitors used to test which suggests that this rat was exposed to the product in very soon. The Committee agreed that this animal is not in the tables on the H Of hypospermatogenesis were included FREQUENCY and only one M nnchen In the high dose group hypospermatogenesis light / sweet did. Expanded minimally lit the building Rmutter was also in the two female rats in the control group and a slight / mild and moderate a conclusion was observed in two and in female rats, respectively in the high dose group. Since the finding was not observed as a treatment in connection with the building Rmutter in the groups was the low and intermediate doses not studied histologically. Since the phase of the cycle Strogenzyklen every woman has not been found at autopsy, it is difficult to determine whether a correlation with the Zyklizit t. The committee, in consultation with an independent Ngigen Reproduktionstoxizit t, with the author of the report that small differences do not agree with the treatment. Studies on the toxicity of t were available for acetochlor ESA and alachlor OXA, acetochlor and alachlor, but not for OXA ESA. Sprague-Dawley rats, 25 animals per group were alachlor ESA in mine L administered S has a probe at a dose of 0, 150, 400 or 1000 mg / kg once per day 6 days to 15 days of the Tr Tet chtigkeit and get the animals were GD 20. All animals survived the mother’s autopsy is scheduled and no findings regarding internal treatment were observed at any dose. Rales were alachlor ESA may need during the tests t Observed resembled that at the time of delivery and one hour after administration. The ERAL were as consistent with an effect lasting irritation no gastric tube with an acidic compound and is not suitable as a basis for a chronic oral reference dose. There were no effects on fetal Streptozotocin growth and survival at any dose and no treatment-related malformations or Entwicklungsst Requirements fetal variations were observed in this study. The Panel concluded that alachlor ESA, no adverse effects in tr Mighty rats or their offspring in each dose. Therefore, the NOAEL for maternal toxicity T and Development.