Conflict process. This is an important issue, because the familiar claim that yarrow analgesic effects, the best was partly due to a reduction of the wall by vinegar Acid induced CONFIRMS has. Moreover, the effect of the extract is not on Ver Changes in locomotor activity t as no Change increased the number of entries Excursions in Hten arm maze or the number of lines crossed was observed in the test. This lack of MOVING DISABLED is compatible with Pires et al. who did not find the Bewegungsaktivit t or adversely caning of motor coordination after the administration of a water-alcohol extract of the aerial parts of Achillea millefolium L. doses of 30 and 300 mg / kg of Achillea millefolium extract in this study at doses of 2 , 43, and the man of 24.3 mg / kg correspond to each. Body weight in view of a person with 70 kg K These doses are 170 mg and 1.7 g. These doses are in the N Hey, what the Europ Pean Medicines Agency for the oral application of yarrow, which is 2 g in 250 ml or twice daily is recommended. Thus, effective doses are to anxiolyticlike effect in this study Like in the HDAC inhibition Herk Mmlichen preparation is used. Interestingly, the angstl Send effect as yarrow in the maze test, h Been saw her after repeated treatment, indicating the lack of tolerance for that purpose under current management organization that is Similar to diazepam. The search for new drugs with anxiolytic ethopharmacological Ans Tze trying to find drugs with a novel mechanism. Benzodiazepine and GABA receptor antagonists were used to evaluate the involvement of GABA / BDZ mechanisms in the anxiolytic effects of such drugs. Picrotoxin does not change as anxiolytic effect of Achillea millefolium In one of the Ma Took the fear of increased Hten maze, w During flumazenil blocked the Erh Increase in the percentage of open arms entries.
This effect of the combination of flumazenil and Achillea millefolium extract in increased Hten maze in the present study is puzzling, because we would expect that the two parameters would be welcomed with open arms have been found to be the same as the trend in several earlier studies, and both heavily loaded on the same factor in factor analysis. However, one can in the literature, few studies that one To have found similar gaps to be seen as a reaction to certain drugs at certain doses, such as 20 mg / kg bretazenil and 10 mg / kg chlordiazepoxide, 10 mg / kg FG 7142 and PK 8165th This situation was a angstl The authors’ conclusion Send or anxiogenic effect as the same treatment. In addition, flumazenil is not a way to release the effects of diazepam in is increased Reverse Hten maze. Flumazenil, and the results of Achillea extract k Nnte angstl Agomelatine 138112-76-2 than one Send action to be taken into consideration, because the percent time spent in the open arms was significantly h Ago than in the control group. The dosage of flunitrazepam binding tested the alleged effect of the extract on Achillea millefolium benzodiazepine binding site. Achillea millefolium extract was not able to move flunitrazepam binding, w Reduced during diazepam flunitrazepam specific binding, suggesting that the extract has no central benzodiazepine Yarrow.