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“We report the current-voltage (I-V) and capacitance-voltage characteristics (C-V) of Ni/n-GaN Schottky diodes. Gallium nitride is a highly promising wide band gap semiconductor for applications in high power electronic and optoelectronic devices which require Schottky barriers for modulating the channel mobile charge. The I-V and C-V characteristics

of the diodes have been measured in the temperature range of 80-400 K with steps of 20 K. Thermal carrier concentration and barrier height versus temperature plots have been obtained from the C-2-V characteristics, and a value of alpha=-1.40 meV/K for temperature coefficient of PCI-32765 mw the barrier height. The modified activation energy plot according to the barrier inhomogeneity model has given the Richardson constant A* as 80 or 85 A/(cm(2) K-2). (C) 2010 American Institute of Physics. [doi: 10.1063/1.3517810]“
“The GSK1838705A aim of the this study is to develop colon targeted drug delivery systems for Ibuprofen using grafted katira gum as a carrier. Polyacrylamide-grafted katira gum was synthesized by grafting acrylamide onto katira gum in presence of varying concentration of ceric ammonium nitrate (CAN) as initiator. Elemental analysis, FTIR, TGA, DTA, DSC, and SEM were used to characterize the grafting

of acrylamide onto katira gum. Matrix tablets containing various proportions of grafted katira gum were prepared by wet granulation method. All the formulations were evaluated for hardness, drug content, swelling index, and in vitro release studies in simulated gastric fluid,

small intestinal fluid, and simulated colonic fluid with and without enzymes. Ibuprofen was used for controlled release study. The drug release mechanism was studied by fitting into Peppas model and was found to be supercase-II transport. Matrix tablets containing 0.3 g of CAN/gm of acrylamide showed optimum value and retained its physical integrity in simulated gastric, small intestinal and colonic fluid, where as other composition disintegrated within Pfizer Licensed Compound Library 2 h of dissolution testing in pH 1.2 buffer, simulated gastric fluid. The results of this study indicates that Ibuprofen matrix tablet containing 60 wt % composition of the above grafted katira gum would be potential formulations in delivering the drug to the colon and the more susceptible for enzymatic degradation. (C) 2010 Wiley Periodicals, Inc. J Appl Polym Sci 119: 2644-2651, 2011″
“The authors compared the outcome in 100 children (61 boys, 39 girls; median age of 10.1 +/- 3.4 years) with aplastic anemia who underwent either immunosuppressive therapy (IST; n = 70) or hematopoietic stem cell transplantation (HSCT; n = 30) between 1998 and 2007. Conditioning regimes for HSCT were a combination of either cyclophosphamide (Cy) with antilymphocyte globulin (ALG) or fludarabine (Flu) with Cy or busulfan (Bu) +/- antithymocyte globulin (ATG).