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“Objective: Maxillofacial injuries in children always present a challenge in respect of their diagnosis and
management. The phenomenal increase in automotives on the road has led to a tremendous rise in the number of road traffic accidents leading to facial injuries, of which children are the most unfortunate selleck chemicals llc victims. The purpose of this retrospective study was to evaluate the epidemiology, etiology and pattern of facial injuries and also to access the most feasible method for the management of facial injuries in children without hampering the facial growth.
Methods: The records and radiographs of 110 patients within the age range of 0-16 years were retrospectively reviewed who have presented with maxillofacial injuries Temsirolimus to our department
from October 2008 to June 2012. The information extracted from patient’s case records included patient’s gender (male/female), age, etiology, fracture type (single fractures and multiple fractures), occlusal status, fracture site and treatment performed.
Results: Patient’s age at the time of accident ranged from 0 to 16 years, with a mean of 6.1 years. 54.54% (n = 60) of the patients were under 6 years (infants and preschool), 31.82% (n = 35) were between 6 and 11 (school age), and 13.64% (n = 15) were between 12 and 16 years (adolescents). Road side accident was the most frequent cause of injury. Most fractures occurred in the mandible (54.54%; n = 60). The fractures with minimal or no occlusal disturbance were managed by liquid diet alone.
Conclusion: We believe that even after so much advancement in surgical techniques and armamentarium, conservative treatment is still the most reliable approach in managing maxillofacial injuries in children. (C) 2013 Elsevier Ireland Ltd. All rights reserved.”
“The project was aimed to develop floating microcapsules (FMs) using combination of a hydrophobic (ethyl cellulose, EC) and hydrophilic polymer
(hydroxy propyl methyl cellulose, HPMC), and to evaluate them. An easy and novel phase separation method was adopted to prepare FMs. Chloroform and paraffin oil were employed as solvent and non-solvent respectively. Five kinetic models were applied to assess and describe the mechanism Selleckchem Ilomastat and pattern of tramadol hydrochloride (TmH) release from FMs and they were subjected to FTIR and XRD to evaluate TmH-HPMC-EC interaction. As EC concentration was increased the retardation in drug release, improvement in flow characteristics and decrease in floating time were observed. Kinetics of drug release was followed by Korsmeyer-Peppas kinetic model. It was concluded that the floating microcapsules of TmH can be produced using phase separation method and they have no drug-polymer interaction. The accelerated stability studies also ensured the physicochemical integrity of FMs.”
“Objective: The cochlear implant has revolutionized functioning with severe-to-profound sensori-neural loss.