European Journal of Human Genetics (2013) 21, 134-142; doi:10.1038/ejhg.2012.129; published online

27 June 2012″
“In this study we evaluated the performance of the oxacillin agar screen test, and agar dilution tests using cefoxitin and oxacillin antimicrobials, to detect meticillin resistance in Staphylococcus aureus isolates. The presence of the mecA gene, detected by PCR, was used as the standard to which agar screen and agar dilution tests were compared. The best performance was obtained using the agar dilution test (99.4 % accuracy) with breakpoints of 4 mu g ml(-1) for oxacillin and 8 mu g ml(-1) for cefoxitin, and using the oxacillin agar screen test. Also, a strong correlation between MIC values of cefoxitin and oxacillin AZD7762 permits the use of either drug for detection of meticillin resistance.”
“Samples of random copolymers consisting of 1-butene modified with a low ethylene content (4, 5, 8% by weight) produced with metallocene catalysts were studied to elucidate the polymorphic behavior of this new class of materials and to characterize them from a structural, morphological, and mechanical point of view. The samples cooled down from the melt are in amorphous phase

and crystallize in a mixture of form I and I or in pure form I with aging time, according Staurosporine mw to the C2 content. Infrared and nuclear magnetic resonance spectroscopy, X-ray diffraction and microscopic techniques were used to follow the changes of the material with aging time and to correlate the structural and morphological ERK inhibition behavior with the peculiar mechanical properties that differentiate

the samples with increasing C2 content. The presence, in the aged samples with higher C2 content, of the pure form I induces the peculiar ability to self-welding and these copolymers combine high flexibility with good elasticity and ductility and can be processed directly or used as modifying agents in polymers. (c) 2013 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2014, 131, 40119.”
“Cerebrospinal fluid (CSF) spectrophotometry for bilirubin is a highly sensitive test in the diagnostic work up of a suspected subarachnoid hemorrhage (SAH).\n\nWe report two cases suffering from an aneurysmal SAH in which extraventricular drainage for acute hydrocephalus was required. Longitudinal analyses of the CSF samples demonstrated that CSF bilirubin was detectable in all cases during the first week, becoming undetectable in one case in the second week. Importantly, CSF ferritin levels rose substantially (> 1,000 ng/ml) after 6 days, peaking around 3,000 ng/ml after 2 weeks (normal upper reference range 12 ng/ml). In both cases blood was visible on the initial CT brain scan, disappearing on a later scan.\n\nCSF ferritin levels may be an important additional laboratory test in the diagnostic work-up of patients with a suspected SAH.