6% were rearfoot strikers (Table 1). Results of chi-square analyses indicate that observed foot strike frequency distributions differ significantly between barefoot and minimally shod runners (X2 = 13.5, df = 2, p < 0.01). The foot strike frequency distribution for barefoot runners in this study differs significantly from those recorded for traditionally shod Baf-A1 road racers in Larson et al. 3 (X2 = 571.63, df = 2, p < 0.0001) and Kasmer et al. 4 (X2 = 751.86, df = 2, p < 0.0001). The foot strike frequency distribution for minimally

shod runners in this study differs significantly from those recorded for traditionally shod road racers in Larson et al. 3 (X2 = 149.2, df = 2, p < 0.0001) and Kasmer et al. 4 (X2 = 265.88, df = 2, p < 0.0001) . Available published data from road race studies conducted to date indicate that approximately 75%–95% of runners land on their rearfoot when initially contacting the ground1, 2, 3 and 4 (Table 1). It is reasonable to presume that the vast majority

of the runners SAHA HDAC in these studies were habitually shod and wore some type of cushioned running shoe during the race, though exact shoe properties might differ among running populations (e.g., racing flats for elite half-marathoners, conventionally cushioned running shoes for recreational marathoners). In support of this presumption, only two of the 936 runners examined by Larson et al.3 were wearing minimally cushioned running shoes (VFF for both; no runners were barefoot). In contrast to the above studies, Lieberman et al.9 observed that initial contact on the midfoot or forefoot is typical for habitually barefoot Kenyan adolescents on a dirt road (88% of foot strikes) and habitually barefoot

American adults in the laboratory (75% of foot strikes). Incidence of rearfoot striking in this same population of habitually barefoot American adults increased from 25% to 50% when shod, and habitually shod Kenyans and Americans tended to rearfoot strike regardless of whether they were wearing shoes.9 These results suggest Thiamine-diphosphate kinase that footwear may influence foot strike patterns. Foot strike distributions for barefoot runners observed here were significantly different from those observed previously for shod road racers. Larson et al.3 and Kasmer et al.4 observed that less than 10% of runners in their samples were symmetrical forefoot or midfoot strikers. In this study, 79.3% of barefoot runners were forefoot or midfoot strikers. This is fairly close to the percentages observed for habitually barefoot American adults and Kenyan adolescents running without shoes.9 It is also similar to the pattern observed for adult male Hadza hunter-gatherers running in sandals or barefoot.16 However, it differs markedly from habitually barefoot Kenyans of the Daasanach tribe,10 Hadza juveniles, and adult Hadza women.16 It is possible that speed, surface properties, and running experience are confounding variables when it comes to comparing foot strike patterns among studies.