On the basis of this intimate association with other cell organelles and the morphometric analysis performed, we suggest that the mobilization of lipid bodies is likely mediated not only by glyoxysomes but also by other catabolic pathways involving the interaction of lipid bodies with either protein storage vacuoles or small Golgi vesicles.”
“Background: Limbic circuitry, especially the anterior cingulate gyrus, has been implicated in the see more pathophysiology and cognitive changes of schizophrenia. Previous diffusion tensor imaging studies have demonstrated that the integrity of the anterior cingulum (AC) is abnormal in schizophrenia. However, the relationship between the abnormal
AC tract integrity and the pathophysiology of schizophrenia has not been fully studied. Methods: We performed a voxelwise group comparison of white matter fractional ARS-1620 nmr anisotropy (FA) by using tract-based spatial statistics in 9 patients with schizophrenia and 9 matched controls. We then measured FA specifically in the AC by using a tract-specific measurement. The latency and amplitude of the mismatch negativity (MMN) were also evaluated in all subjects. Results: In patients with schizophrenia, tract-based
spatial statistics showed a reduction in FA in broad white matter areas, including the bilateral AC, compared with controls. Tract-specific measurements confirmed the specific reduction of FA in the region of the bilateral find more AC. The decreased FA in the AC was correlated with prolonged MMN latency in the patient group. Conclusion: Our study of AC structure and electrophysiological changes in schizophrenia suggest that the disruption of limbic-cortical structural networks may be part of the neural basis underlying the changes in MMN in schizophrenia. (C) 2013 S. Karger AG, Basel”
“Objective: Patients with juxtarenal, pararenal, or thoracoabdominal aneurysms require complex
surgical open repair, which is associated with increased mortality and morbidity. The “”chimney graft”" or “”snorkel”" technique has evolved as a potential alternative to fenestrated and side-branched endografts. The purpose of this study is to review all published reports on chimney graft (CG) technique involving visceral vessels and investigate the safety and efficacy of the technique.
Methods: Studies were included in the present review if visceral revascularization during endovascular treatment of aortic pathologies was achieved via a CG implantation. Reports on the chimney technique for aortic arch branches revascularization were excluded. A multiple electronic health database search was performed on all articles published until April 2011.
Results: The electronic literature search yielded 15 reports that fulfilled the inclusion criteria. A total of 93 patients (81.3% male; mean age, 71.9 +/- 0.9 years) were analyzed. In 77.