Ethics: The National Ethics Committee (NZ) approved this study. NTY/10/01/008. All participants gave written informed consent before data collection began. Competing interests: Nil. Support: AUT Internal Contestable Grant. Neurology Group of the New Zealand Society of Physiotherapists. We are grateful to all those who participated in this study. “
“Summary of: Eakin

EG, et al (2013) Six-month outcomes from living well with diabetes: a randomized trial of a telephone-delivered weight DNA Synthesis inhibitor loss and physical activity intervention to improve glycemic control. Ann Behav Med [Epub ahead of print doi.10.1007/s12160-013-9498-2.] [Prepared by Kylie Hill, CAP Editor.] Question: Does a telephone-delivered intervention aimed at increasing physical activity and improving dietary intake serve to reduce weight, increase physical activity and improve glycaemic control in people with Type 2 diabetes? Design: Randomised controlled trial with blinded outcome assessors. Setting: The participants’ Bortezomib order homes in the city of Logan, Australia. Participants: People were eligible to participate if they were aged 20–75 years, had Type 2 diabetes, were inactive, had a body mass index ≥ 25 kg/m2, were

not using weight loss medication, and had no previous or planned bariatric surgery. Randomisation, using the minimisation method, allocated 151 participants each to the intervention and control groups. Interventions: Over a six-month period, the intervention involved 14 phone calls which comprised motivational interviewing, focusing on the benefits of weight loss and lifestyle changes together with goal setting to achieve specific Non-specific serine/threonine protein kinase targets related to weight loss, physical activity, and dietary intake. Participants were also provided with a workbook, a pedometer (to monitor daily step counts), and a set of digital scales (to monitor body weight). They were encouraged to achieve weight loss through exercise (≥ 210 minute/week) and a reduction in energy and total fat intake. The control group received generic self-management

brochures about Type 2 diabetes. Outcome measures: The primary outcomes were weight loss, accelerometer-derived moderate to vigorous physical activity, and glycosylated haemoglobin (HbA1c). Results: A total of 279 participants completed the study. On completion of the intervention period, compared with those in control group, those in the intervention group achieved greater weight loss (−1.1%, 95% CI −1.9 to −0.3). This betweengroup difference was equal to −1.1 kg. The intervention group also performed more physical activity (30%, 95% CI 8 to 57). This between-group difference was equal to 31 minutes of moderate to vigorous physical activity per week. There were no differences in HbA1c.