This finding in our sample seems to confirm the conclusions that blood pressure responses to varying positions are comparable irrespective of the gender and race of the participants.12 Perhaps gender is not a personal individual factor that can influence or determine differences in cardiovascular responses following varying postures. There are some limitations to this study, which should be noted when interpreting the findings. First, the external validity of the study may be

low because the participants were recruited www.selleckchem.com/products/Cyclopamine.html through a convenience sampling technique and were limited to people with a potentially higher educational status (university students and Inhibitors,research,lifescience,medical staff of a teaching hospital). Second, the measurement was not performed at a similar time for all the participants, and it is possible for cardiovascular responses to inversion

to vary at different time points Inhibitors,research,lifescience,medical during the day when the measurements are taken. Also, the environmental temperature during the procedure was not measured, which may preclude the generalization of our findings to different seasons in Maiduguri, Nigeria. Despite these Inhibitors,research,lifescience,medical limitations, however, the findings from the present study can be used as a basis for further exploratory studies on the cardiovascular responses to inversion during Muslim prayers, and can also elucidate on the body of knowledge on the effects of postural changes on cardiovascular responses in the general population. Conclusion This study revealed a significant decrease in systolic and diastolic blood pressures and an increase in pulse rate at different time points during Sujood. Also, our findings showed no significant gender difference in the effect of Sujood on cardiovascular parameters at different points Inhibitors,research,lifescience,medical in time. These findings Inhibitors,research,lifescience,medical indicate that the blood pressure of the healthy

subjects was not elevated within the first three minutes into Sujood and suggest that there may be no adverse effect or danger attributable to this prayer position. The present study is confirmation that Sujood is safe and no adverse cardiovascular effect can be expected to arise from it in the usual obligatory Muslim prayers or even longer durations for which ADAMTS5 the unusual or periodic non-obligatory prayers are held. Conflict of Interest: None declared.
Background: It was hypothesized that the use of Pentoxifylline would increase arterial O2 saturation and increase exercise tolerance in patients with Chronic Obstructive Pulmonary Disease (COPD). Methods: We tested this hypothesis in 23 patients with COPD and pulmonary hypertension. Patients were randomized to receive Pentoxifylline or placebo, each for a 12-week period, in a prospective, double-blind study to assess the effects of Pentoxifylline on oxygen saturation and exercise tolerance via pulse oximetry and the 6-Minute Walk Test (6MWT). Results: At the end of the 12 weeks, the six-minute walk distance rose from 351.